How Are GLP-1 and GLP/GIP Medications Different?

Plus-sized woman meeting with doctor to discuss semaglutide or tirzepatide for weight loss

Medications like semaglutide and tirzepatide are popular options for medical weight loss, but figuring out which one fits your needs isn’t always simple.

At Weight Success Centers, founded by board-certified bariatric surgeon Dr. Wilfred Aguila, we make it easy to understand your weight loss options. We’ve partnered with providers in Westchase, Brandon, and Trinity, Florida, who will guide you toward the option that’s right for you.

What Is Semaglutide?

Semaglutide is a medication known as a GLP-1 receptor agonist, meaning it works by mimicking a hormone your body naturally produces. It’s FDA-approved specifically for chronic weight management, helping you lose weight by reducing appetite, slowing digestion, and improving blood sugar levels. 

Many people lose a lot of weight with semaglutide, and it’s a popular option to try when dieting alone doesn’t work well.

Semaglutide is typically administered at home with weekly injections. If you’ve struggled with managing hunger or portion control, semaglutide might be an excellent fit.

Understanding Tirzepatide

Tirzepatide is newer to the scene but has quickly gained attention for its unique approach. Unlike semaglutide, tirzepatide targets two hormone receptors: GLP-1 and GIP. This dual action reduces hunger and improves blood sugar management. It may also lead to even greater weight loss for some individuals.

Early research shows tirzepatide can offer impressive results, particularly for people who have struggled with weight-related metabolic issues. It’s self-administered once weekly, similar to semaglutide, and has quickly become appealing to those who want more powerful weight-loss effects.

Main Differences Between Semaglutide and Tirzepatide

Here’s a clear side-by-side comparison to help you see exactly how these medications differ:

Semaglutide:

  • Targets one hormone pathway (GLP-1)
  • Proven effective for significant weight loss
  • Ideal if your primary goal is appetite control and steady weight loss

Tirzepatide:

  • Targets two hormone pathways (GLP-1 and GIP)
  • May result in greater weight loss due to dual action
  • Best if you’re looking for a more potent option, especially with metabolic issues

Choosing the best option depends on your situation. Your health goals, medical history, and preferences all matter.

Ready for Personalized Help?

Weight Success Centers knows that your journey is unique. Your provider will happily answer your questions and help you make a choice that works for your goals. To schedule a consultation in Trinity, call 727-359-2487. For Brandon, call 813-603-7804, or for Westchase, call 727-755-3852.

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Important Notice: Weight Success Centers and Zen Medi Spa are licensed medical practices offering in-person consultations and treatments only. We do not provide online prescriptions or operate as an internet pharmacy. To receive medical care, please schedule an appointment at our clinic to meet with a healthcare provider.

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